Transcriptional scaffolds for heterochromatin assembly.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19239883.
- Also identified by DOI 10.1016/j.cell.2009.02.004 and PMC identifier 6309854.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Heterochromatin is dynamically regulated during the cell cycle and in response to developmental signals. Recent findings from diverse systems suggest an extensive role for transcription in the assembly of heterochromatin, highlighting the emerging theme that transcription and noncoding RNAs can provide the initial scaffold for the formation of heterochromatin, which serves as a versatile recruiting platform for diverse factors involved in many cellular processes.
Medical subject headings
- Chromatin Assembly and Disassembly
- Heterochromatin
- RNA, Untranslated