On the path to seeking novel radiosensitizers.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19251086.
- Also identified by DOI 10.1016/j.ijrobp.2008.12.002.
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Abstract
Radiation therapy is a highly effective cancer treatment modality, and extensive investigations have been undertaken over the years to augment its efficacy in the clinic. This review summarizes the current understanding of the biologic bases underpinning many of the clinically used radiosensitizers. In addition, this review illustrates how the advent of innovative, high-throughput technologies with integration of different disciplines could be harnessed for an expeditious discovery process for novel radiosensitizers, providing an exciting future for such pursuits in radiation biology and oncology.
Medical subject headings
- Neoplasms
- Radiation-Sensitizing Agents