Quantum dots-based immunofluorescence technology for the quantitative determination of HER2 expression in breast cancer.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19251316.
- Also identified by DOI 10.1016/j.biomaterials.2009.02.010.
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Abstract
HER2 detection is important for breast cancer (BC) treatment and prognosis, but the detection methods currently used have some disadvantages. Quantum dots (QDs)-based probes provide a potentially important new method for HER2 detection in clinical practice. This potential is examined in this paper. A QDs HER2 probe kit and QDs image acquisition and analysis software were developed and applied to 94 clinical samples of BC. Compared to conventional immunohistochemistry techniques, this method provided a superior accurate and sensitive method for the detection of HER2 in clinical breast cancer diagnosis.
Medical subject headings
- Breast Neoplasms
- Genes, erbB-2
- Quantum Dots