A web server for inferring the human N-acetyltransferase-2 (NAT2) enzymatic phenotype from NAT2 genotype.
Where this comes from
- Record sourced from PubMed, PMID 19261719.
- Also identified by DOI 10.1093/bioinformatics/btp121 and PMC identifier 2672629.
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Abstract
N-acetyltransferase-2 (NAT2) is an important enzyme that catalyzes the acetylation of aromatic and heterocyclic amine carcinogens. Individuals in human populations are divided into three NAT2 acetylator phenotypes: slow, rapid and intermediate. NAT2PRED is a web server that implements a supervised pattern recognition method to infer NAT2 phenotype from SNPs found in NAT2 gene positions 282, 341, 481, 590, 803 and 857. The web server can be used for a fast determination of NAT2 phenotypes in genetic screens. Freely available at http://nat2pred.rit.albany.edu. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Arylamine N-Acetyltransferase
- Polymorphism, Single Nucleotide
- Software