Key endothelial signals required for hematopoietic recovery.

Porter, Rebecca L; Calvi, Laura M · Cell Stem Cell · 2009

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Hooper et al. (2009) use a combination of immunohistochemistry and flow cytometry to characterize the bone marrow vasculature both before and after injury. The authors demonstrate that recovery of normal hematopoiesis after myelosuppressive insult is dependent upon endothelial VEGFR2.

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