A radical bailout strategy for cancer stem cells.

Tothova, Zuzana; Gilliland, D Gary · Cell Stem Cell · 2009

basic_science · Level V

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Abstract

In a recent issue of Nature, Diehn et al. (2009) demonstrate that breast cancer stem cells (CSCs) maintain lower levels of reactive oxygen species (ROS) than their nontumorigenic counterparts. Their studies provide a link between the management of ROS by CSCs and enhanced tumor radioresistance.

Medical subject headings