Tuberculosis complicating hepatitis C treatment in HIV-infected patients.

Pérez-Elías, Maria Jesús; García-San Miguel, Lucía; González García, Juan; Montes Ramírez, Maria Luisa; Muriel, Alfonso; Machín-Lázaro, Jose M; Martínez-Baltanás, Aida; Zamora, Francisco et al. · Clin Infect Dis · 2009

retrospective_cohort · Level III

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Abstract

Tuberculosis characteristics and incidence were assessed among patients with concurrent human immunodeficiency virus infection and chronic hepatitis C virus infection who were receiving interferon-based therapy at 3 hospitals in Spain. Four of 570 patients (0.7 cases per 100 person-years; 95% confidence interval, 0.19-1.78 cases per 100 person-years) received a diagnosis of tuberculosis; all of them presented with a decrease in CD4+ cell count before diagnosis, and 3 of them received a delayed diagnosis. After tuberculosis treatment, all patients were cured.

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