A novel parallel approach to the likelihood-based estimation of admixture in population genetics.

Giovannini, Ambra; Zanghirati, Gaetano; Beaumont, Mark A; Chikhi, Lounès; Barbujani, Guido · Bioinformatics · 2009

basic_science · Level V

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Abstract

Inferring population admixture from genetic data and quantifying it is a difficult but crucial task in evolutionary and conservation biology. Unfortunately state-of-the-art probabilistic approaches are computationally demanding. Effectively exploiting the computational power of modern multiprocessor systems can thus have a positive impact to Monte Carlo-based simulation of admixture modeling. A novel parallel approach is briefly described and promising results on its message passing interface (MPI)-based C++ implementation are reported. The software package parLEA is freely available at (http://dm.unife.it/parlea).

Medical subject headings