Plasma 25,OH vitamin D concentrations are not associated with rheumatoid arthritis (RA)-related autoantibodies in individuals at elevated risk for RA.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 19286844.
- Also identified by DOI 10.3899/jrheum.080764 and PMC identifier 2745328.
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Abstract
To evaluate the association between rheumatoid arthritis (RA)-related autoantibodies and plasma 25,OH vitamin D in subjects at risk for RA. In 1210 subjects without RA, 76 were positive for anti-cyclic citrullinated peptide antibodies or for at least 2 rheumatoid factors (RF; by nephelometry: RF-IgM, RF-IgG, RF-IgA). 25,OH vitamin D was measured in these cases and 154 autoantibody-negative controls from this cohort. 25,OH vitamin D levels did not differ between cases and controls (adjusted OR 1.23, 95% CI 0.93-1.63). Vitamin D concentrations are not associated with RA-related autoimmunity in unaffected subjects at increased risk for RA.
Medical subject headings
- Arthritis, Rheumatoid
- Peptides, Cyclic
- Rheumatoid Factor
- Vitamin D