A gate keeper for axonal transport.

Xiao, Shaohua; Jan, Lily Yeh · Cell · 2009

basic_science · Level V

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Abstract

The axon and dendritic arbor of neurons require different sets of membrane proteins to carry out their functions. In this issue, Song et al. (2009) describe how a cytoplasmic diffusion barrier in the axon initial segment of rat hippocampal neurons ensures that only axonal (and not dendritic) membrane proteins enter the axon.

Medical subject headings