GetBonNie for building, analyzing and sharing rule-based models.

Hu, Bin; Matthew Fricke, G; Faeder, James R; Posner, Richard G; Hlavacek, William S · Bioinformatics · 2009

other · Level V

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Abstract

GetBonNie is a web-based application for building, analyzing and sharing rule-based models encoded in the BioNetGen language (BNGL). Tools accessible within the GetBonNie environment include (i) an applet for drawing graphs that correspond to BNGL code; (ii) a network-generation engine for translating a set of rules into a chemical reaction network; (iii) simulation engines that implement generate-first, on-the-fly and network-free methods for simulating rule-based models; and (iv) a database for sharing models, parameter values, annotations, simulation tasks and results. GetBonNie is free at (http://getbonnie.org).

Medical subject headings