Harnessing nature's toolbox: regulatory elements for synthetic biology.

Boyle, Patrick M; Silver, Pamela A · J R Soc Interface · 2009

review · Level V

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Abstract

Synthetic biologists seek to engineer complex biological systems composed of modular elements. Achieving higher complexity in engineered biological organisms will require manipulating numerous systems of biological regulation: transcription; RNA interactions; protein signalling; and metabolic fluxes, among others. Exploiting the natural modularity at each level of biological regulation will promote the development of standardized tools for designing biological systems.

Medical subject headings