BMI and diabetes risk in Singaporean Chinese.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 19324946.
- Also identified by DOI 10.2337/dc08-1674 and PMC identifier 2681015.
- Licence recorded as CC BY-NC-ND.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Increased BMI is a robust risk factor for type 2 diabetes. Paradoxically, South Asians have relatively low BMIs despite their high prevalence of type 2 diabetes. We examined the association between BMI and incident type 2 diabetes because detailed prospective cohort data on this topic in Asians are scarce. This study was a prospective analysis of 37,091 men and women aged 45-74 years in the Singapore Chinese Health Study, using Cox regression analysis. Risk of incident type 2 diabetes significantly increased beginning with BMIs 18.5-23.0 kg/m(2)(relative risk 2.47 [95% CI 1.75-3.48]) and continued in a monotonic fashion across the spectrum of BMI. Results were stronger for younger than for older adults. BMIs considered lean and normal in Singaporean Chinese are strongly associated with increased risk of incident type 2 diabetes. This association weakened with advanced age but remained significant.
Medical subject headings
- Asian People
- Body Mass Index
- Diabetes Mellitus