Use of non-collagen markers in osteoporosis studies.

Parviainen, M T; Pirskanen, A; Mahonen, A; Alhava, E M; Mäenpää, P H · Calcif Tissue Int · 1991

review · Level V

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Abstract

Clinical and research laboratories routinely measure various hormonal and nonhormonal parameters of calcium and phosphorus metabolism, and markers of bone turnover. Such measurements may help clinical decision-making relating to metabolic bone disease and osteoporosis. Molecular biological and cell-culture techniques are being used in basic biochemical research on bone-cell metabolism. Results may aid understanding of normal and abnormal regulation of the bone-cell metabolism, and thus provide further insights relating to the diagnosis and prevention of osteoporosis.

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