Prevention of first-episode depression: progress and potential.

Robinson, Robert G; Jorge, Ricardo E · Br J Psychiatry · 2009

editorial · Level V

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Abstract

Preventive intervention for first-episode depression is an exciting, emerging field. Many questions remain, however. Should we target patients who have sub-syndromal symptom elevations (i.e. indicated intervention) or should we intervene in high-risk groups (i.e. selective intervention)? Furthermore, should primary outcomes be incident depressions or long-term decreases in morbidity or mortality?

Medical subject headings