Recreating stem cells: a novel entrance to the fountain of youth.

te Riele, Hein · Cell Stem Cell · 2009

editorial · Level V

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Abstract

Differentiated cells can be reprogrammed to form pluripotent embryonic stem cell-like cells by ectopic expression of four transcription factors. In this issue of Cell Stem Cell, Liu et al. (2009) demonstrate that a similar transition can be achieved by culturing retinoblastoma-deficient mouse embryonic fibroblasts in suspension.

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