A new twist on brown fat metabolism.

Wallberg-Henriksson, Harriet; Zierath, Juleen R · Cell · 2009

basic_science · Level V

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Abstract

The transcriptional coactivator PGC-1alpha promotes mitochondrial biogenesis and thermogenic programs in brown adipose tissue. Pan et al. (2009) identify the transcription factor twist-1 as a negative feedback regulator of PGC-1alpha.

Medical subject headings