Neutrophil sandwiches injure the microcirculation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19350004.
- Also identified by DOI 10.1038/nm0409-364 and PMC identifier 2719794.
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Abstract
Experiments in two mouse models of thromboinflammatory disease show how neutrophils stick to red blood cells and platelets—leading to reduced blood flow and damage to the microcirculation. Polarized expression of α<sub>M</sub>β<sub>2</sub> integrins on neutrophils helps set the process in motion (pages 384−391).
Medical subject headings
- Erythrocytes
- Inflammation
- Microcirculation
- Neutrophils
- Transfusion Reaction