IgE-mediated fungal allergy in allergic fungal sinusitis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19358255.
- Also identified by DOI 10.1002/lary.20170.
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Abstract
This review will address the current knowledge of the pathogenic mechanisms in allergic fungal sinusitis (AFS) and the basis for the current classification of a subgroup of chronic rhinosinusitis patients. Special attention is directed to the role of immunoglobulin E (IgE)-mediated fungal allergy in the pathogenesis of AFS. Concepts relating to the mucosal inflammatory response are introduced, as a knowledge of the reactions of the sinus mucosal cells can lead to a better understanding of the mechanisms perpetuating and maintaining the chronic inflammation. Laryngoscope, 2009.
Medical subject headings
- Eosinophilia
- Fungi
- Immunoglobulin E
- Rhinitis, Allergic, Perennial
- Sinusitis