Adalimumab treatment of life-threatening tuberculosis.

Wallis, Robert S; van Vuuren, Cloete; Potgieter, Samantha · Clin Infect Dis · 2009

case_report · Level V

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Abstract

Most guidelines call for the discontinuation of treatment with tumor necrosis factor blockers in patients who develop tuberculosis. We report a case of life-threatening tuberculosis paradoxical reaction involving the lungs caused by withdrawal of the anti-tumor necrosis factor antibody adalimumab. Clinical improvement occurred only after resumption of adalimumab treatment.

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