Fallen immortals.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19379684.
- Also identified by DOI 10.1016/j.cell.2009.04.008.
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Abstract
The memory of somatic cell gene expression is reset in the germline in a process that is accompanied by dramatic changes in chromatin modifications. In this issue, Katz et al. (2009) show that the histone demethylase Lsd1/Spr-5 may participate in this resetting process in the worm, thereby preventing a decline in germ cell epigenetic stability and viability over ensuing generations.
Medical subject headings
- Caenorhabditis elegans
- Epigenesis, Genetic
- Germ Cells