Ubiquitin connects with planar cell polarity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19379687.
- Also identified by DOI 10.1016/j.cell.2009.04.002.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Planar cell polarity (PCP) regulates the orientation of cells in epithelia and of mesenchymal cells during gastrulation. In this issue, Narimatsu et al. (2009) report that the Smurf E3 ubiquitin ligases are required for localized protein degradation of a core PCP factor to generate cellular asymmetry.
Medical subject headings
- Cell Polarity
- Cochlea
- Ubiquitin-Protein Ligases