Recurrent Burkholderia infection in patients with chronic granulomatous disease: 11-year experience at a large referral center.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 19400745.
- Also identified by DOI 10.1086/598937 and PMC identifier 2850592.
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Abstract
The epidemiology of Burkholderia infection in persons with chronic granulomatous disease is poorly understood. We used species-specific polymerase chain reaction-based assays and genotyping analyses to identify 32 strains representing 9 Burkholderia species among 50 isolates recovered from 18 patients with chronic granulomatous disease. We found that recurrent pulmonary infection with distinct Burkholderia strains is common in chronic granulomatous disease.
Medical subject headings
- Burkholderia
- Burkholderia Infections
- Granulomatous Disease, Chronic
- Pneumonia, Bacterial