An outbreak of postoperative gram-negative bacterial endophthalmitis associated with contaminated trypan blue ophthalmic solution.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 19400746.
- Also identified by DOI 10.1086/598938.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report 6 cases of postsurgical endophthalmitis due to gram-negative bacteria associated with contaminated trypan blue dye from a compounding pharmacy. Unopened trypan blue syringes yielded Pseudomonas aeruginosa and Burkholderia cepacia complex on culture, with pulsed-field gel electrophoresis patterns indistinguishable from patient isolates. Contamination of compounded medications should be considered when investigating outbreaks of postoperative endophthalmitis.
Medical subject headings
- Cross Infection
- Disease Outbreaks
- Drug Contamination
- Endophthalmitis
- Gram-Negative Bacterial Infections
- Ophthalmic Solutions
- Surgical Wound Infection