Type 2 diabetes prevention in the real world: three-year results of the GOAL lifestyle implementation trial.

Absetz, Pilvikki; Oldenburg, Brian; Hankonen, Nelli; Valve, Raisa; Heinonen, Heikki; Nissinen, Aulikki; Fogelholm, Mikael; Talja, Martti et al. · Diabetes Care · 2009

prospective_cohort · Level II

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Abstract

OBJECTIVE We study the effectiveness of the GOAL Lifestyle Implementation Trial at the 36-month follow-up. RESEARCH DESIGN AND METHODS Participants (n = 352, type 2 diabetes risk score FINDRISC = 16.2 +/- 3.3, BMI 32.6 +/- 5.0 kg/m(2)) received six lifestyle counseling sessions over 8 months. Measurements were at baseline, 12 months (88.6%), and 36 months (77.0%). RESULTS Statistically significant risk reduction at 12 months was maintained at 36 months in weight (-1.0 +/- 5.6 kg), BMI (-0.5 +/- 2.1 kg/m(2)), and serum total cholesterol (-0.4 +/- 1.1 mmol/l). CONCLUSIONS Maintenance of risk reduction in this "real world" trial proves the intervention's potential for significant public health impact.

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