Specifying mouse embryonic germ cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19410535.
- Also identified by DOI 10.1016/j.cell.2009.04.016.
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Abstract
Male germ cells are induced to form from the epiblast of the mouse embryo by a combination of WNT and bone morphogenetic protein signals. Ohinata et al. (2009) now clarify the steps of mouse germ cell formation and use this genetic insight to direct the specification and differentiation of germline progenitor cells in vitro.
Medical subject headings
- Cell Differentiation
- Germ Cells
- Mesoderm
- Stem Cells