Opening windows to the genome.

Whitehouse, Iestyn; Tsukiyama, Toshio · Cell · 2009

basic_science · Level V

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Abstract

Recent mapping of nucleosome positioning has added a new dimension to the study of transcriptional regulation. Hartley and Madhani (2009) now demonstrate the power of this approach and show that a chromatin regulator alters nucleosome positioning in the promoters of a large number of genes in the budding yeast Saccharomyces cerevisiae.

Medical subject headings