Frodos found: Behold the CENP-a "Ring" bearers.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19410539.
- Also identified by DOI 10.1016/j.cell.2009.04.035 and PMC identifier 3192489.
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Abstract
CENP-A is a histone H3-like protein specific to centromeres that is essential for kinetochore formation and accurate chromosome segregation in eukaryotes. Recent studies (Dunleavy et al., 2009; Foltz et al., 2009; Perpelescu et al., 2009; Pidoux et al., 2009; Williams et al., 2009) analyze CENP-A binding proteins required for the recruitment of CENP-A to centromeres in humans and in fission yeast, bringing us closer to understanding how centromere identity is faithfully propagated.
Medical subject headings
- Autoantigens
- Chromosomal Proteins, Non-Histone
- Chromosome Segregation
- Schizosaccharomyces