Safety implications of high-field MRI: actuation of endogenous magnetic iron oxides in the human body.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19412550.
- Also identified by DOI 10.1371/journal.pone.0005431 and PMC identifier 2673027.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
BACKGROUND: Magnetic Resonance Imaging scanners have become ubiquitous in hospitals and high-field systems (greater than 3 Tesla) are becoming increasingly common. In light of recent European Union moves to limit high-field exposure for those working with MRI scanners, we have evaluated the potential for detrimental cellular effects via nanomagnetic actuation of endogenous iron oxides in the body. METHODOLOGY: Theoretical models and experimental data on the composition and magnetic properties of endogenous iron oxides in human tissue were used to analyze the forces on iron oxide particles. PRINCIPAL FINDING AND CONCLUSIONS: Results show that, even at 9.4 Tesla, forces on these particles are unlikely to disrupt normal cellular function via nanomagnetic actuation.
Medical subject headings
- Ferric Compounds
- Magnetic Resonance Imaging
- Magnetics