Allergic hypersensitivity to topical and systemic corticosteroids: a review.

Baeck, M; Marot, L; Nicolas, J-F; Pilette, C; Tennstedt, D; Goossens, A · Allergy · 2009

review · Level V

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Abstract

Corticosteroids, which are potent anti-inflammatory and immunomodulator agents used in the treatment of various inflammatory diseases including allergic diseases, can in some cases produce immediate or delayed hypersensitivity reactions. This review summarizes the epidemiological and clinical characteristics of such reactions, including related diagnostic issues. It also presents a detailed analysis of the proposed immunological mechanisms including underlying cross-reactions.

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