Astemizole-induced cardiac conduction disturbances in a child.

Tobin, J R; Doyle, T P; Ackerman, A D; Brenner, J I · JAMA · 1991

case_report · Level V

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Abstract

The newly available antihistamine astemizole (Hismanal) has been previously associated with hemodynamically significant cardiac tachydysrhythmias. We describe a 3-year-old girl who developed multiple different cardiac dysrhythmias after an astemizole overdose. No hemodynamic compromise occurred, and the electrocardiogram returned to normal without use of antiarrhythmic agents within 7 hours.

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