The neurofibroma cell of origin: SKPs expand the playing field.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 19427284.
- Also identified by DOI 10.1016/j.stem.2009.04.010.
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Abstract
Mounting evidence suggests that stem/progenitor cells may be the cells of origin for many tumor types. In this issue of Cell Stem Cell, Le et al. (2009) demonstrate that skin-derived precursors (SKPs) can initiate dermal neurofibromas and highlight the importance of the microenvironment in the formation of this complex tumor.
Medical subject headings
- Neurofibroma
- Skin
- Stem Cells