Screening for novel regulators of embryonic stem cell identity.

Subramanian, Vidya; Klattenhoff, Carla A; Boyer, Laurie A · Cell Stem Cell · 2009

basic_science · Level V

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Abstract

Two recent studies, including one in this issue of Cell Stem Cell, have identified novel regulators of embryonic stem cell (ESC) self-renewal using genome-wide RNAi screens in mouse ESCs (Ding et al., 2009; Hu et al., 2009) and have further expanded the repertoire of factors that regulate ESC identity.

Medical subject headings