Presence of a multidrug-resistance mutation in an HIV-2 variant infecting a treatment-naive individual in Caio, Guinea Bissau.

Jallow, Sabelle; Vincent, Tim; Leligdowicz, Aleksandra; De Silva, Thushan; Van Tienen, Carla; Alabi, Abraham; Sarge-Njie, Ramu; Aaby, Peter et al. · Clin Infect Dis · 2009

case_report · Level V

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Abstract

We report the possible transmission of drug-resistant human immunodeficiency virus type 2. A 66-year-old woman from rural Guinea Bissau who had no obvious antiretroviral exposure was found to harbor a variant with the multidrug-resistance mutation Q151M. Finding this mutation among a drug-naive population presents an important public health issue that needs to be addressed for treatment to be effective.

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