Autonomous thyroid adenoma: only an adulthood disease?
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 19446102.
- Also identified by DOI 10.1016/j.jpeds.2008.12.019.
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Abstract
We identified somatic activating thyrotropin-receptor gene mutations within autonomous thyroid nodules (ATN) in 2 girls with 1 ATN and in 1 girl with 3 ATN. A fourth patient had a somatic activating gene mutation of the alpha-subunit of the stimulating G-protein in 2 ATN. Activating somatic mutations in ATN can cause non-autoimmune hyperthyroidism in children.
Medical subject headings
- Thyroid Neoplasms