High-dose oral baclofen: experience in patients with multiple sclerosis.

Smith, C R; LaRocca, N G; Giesser, B S; Scheinberg, L C · Neurology · 1991

retrospective_cohort · Level III

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Abstract

We reviewed a 10% random sample of charts from an outpatient clinic for multiple sclerosis to determine the frequency with which baclofen was prescribed for spasticity in high doses (greater than 80 mg/d). About 20% of patients had taken high-dose baclofen, and 15% were still receiving a high dose. Taking a high dose was not associated with discontinuing treatment.

Medical subject headings