End point assessment in gliomas: novel treatments limit usefulness of classical Macdonald's Criteria.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19451418.
- Also identified by DOI 10.1200/JCO.2009.22.4998 and PMC identifier 2702230.
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Abstract
Recent trials in glioma have revealed significant limitations in the end points used. This requires a critical and comprehensive review of how brain tumor trials are conducted, particularly of which end points are defined and how response and progression are defined.
Medical subject headings
- Brain Neoplasms
- Disease Progression
- Glioma
- Research Design