Nasopharyngeal colonization by nontypeable Hemophilus influenzae in children: the effect of serum bactericidal antibody.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 1945426.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The effect of serum bactericidal antibody on colonization with NTHI was studied in 26 children. Serum bactericidal antibody did not prevent colonization with NTHI in the nasopharynx. Antibody was detected in 53% before, 91% during, and 100% after documented colonization. The log titer of antibody was significantly higher during (1.18 +/- 0.56), p less than 0.002; and after (1.31 +/- 0.29), p greater than 0.001 compared to before colonization (0.49 +/- 0.51). The roles of secretory IgA and normal nasopharyngeal flora in inhibiting pathogenic bacteria are discussed.
Medical subject headings
- Antibodies, Bacterial
- Haemophilus influenzae
- Nasopharynx