Cemented total hip arthroplasty in a patient with alpha-mannosidosis: a case report.

Desai, Aravind S; Dramis, Asterios; Board, Timothy N; Kay, Peter R · Hip Int · 2009

case_report · Level V

Where this comes from

Abstract

Mannosidosis is an extremely rare genetic disease occurring due to deficiency of the lysosomal enzyme, alpha-mannosidase. Patients with this disorder often suffer from musculoskeletal abnormalities and muscular weakness leading to joint destruction and severe morbidity along with other major systems involvement. We present here such a case of a 27-year-old male that highlights the challenges in management of hip joint destruction secondary to Mannosidosis.

Medical subject headings

Anatomy