Serum sickness-like reaction associated with inactivated influenza vaccination among Thai health care personnel: risk factors and outcomes.

Apisarnthanarak, Anucha; Uyeki, Timothy M; Miller, Elaine R; Mundy, Linda M · Clin Infect Dis · 2009

retrospective_cohort · Level III

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Abstract

Fourteen (3%) of 495 Thai health care personnel were identified as having a serum sickness-like reaction in 2008 after receipt of inactivated influenza vaccine manufactured in Thailand. These health care personnel experienced fever, myalgia, centrifugal arthralgias, and injection site erythema. A history of allergic reactions to food or drugs (adjusted odds ratio, 5.9; 95% confidence interval, 1.54-25.4) was independently associated with a serum sickness-like reaction.

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