Pitfalls, problems, and progress in bronchopulmonary dysplasia.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19482769.
- Also identified by DOI 10.1542/peds.2008-1962.
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Abstract
Bronchopulmonary dysplasia is a chronic lung disease associated with premature birth and characterized by early lung injury. In this review we discuss some pitfalls, problems, and progress in this condition over the last decade, focusing mainly on the last 5 years, limited to studies in human neonates. Changes in the definition, pathogenesis, genetic susceptibility, and recent biomarkers associated with bronchopulmonary dysplasia will be discussed. Progress in current management strategies, along with novel approaches/therapies, will be critically appraised. Finally, recent data on long-term pulmonary and neurodevelopmental outcomes of infants with bronchopulmonary dysplasia will be summarized.
Medical subject headings
- Bronchopulmonary Dysplasia