At loose ends: resecting a double-strand break.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19490890.
- Also identified by DOI 10.1016/j.cell.2009.05.007 and PMC identifier 3977653.
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Abstract
Double-strand break (DSB) repair is critical for maintaining genomic integrity and requires the processing of the 5' DSB ends. Recent studies have shed light on the mechanism and regulation of DNA end processing during DSB repair by homologous recombination.
Medical subject headings
- DNA Breaks, Double-Stranded
- DNA Repair