Retrofitting fat metabolism.

Pei, Liming; Evans, Ronald M · Cell Metab · 2009

Level V

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Abstract

In this issue of Cell Metabolism, Liao and colleagues have applied a novel synthetic approach to fight obesity in animals by engineering the plant glyoxylate shunt in vivo (Dean et al., 2009). The idea of introducing an entirely foreign metabolic pathway opens up opportunities for understanding metabolism and creating novel potential therapeutic approaches.

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