Obesity genes-it's all about the parents!

Farooqi, Sadaf · Cell Metab · 2009

other · Level V

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Abstract

Maternal inheritance of mutations in the GNAS1 gene is associated with obesity in humans, but the mechanism involved is unknown. In this issue, Chen et al. (2009) have generated mice with brain specific deletion of either the maternal or paternal allele to trace the origin of the phenotype.

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