Smoothening the controversial role of hedgehog in hematopoiesis.

Merchant, Akil A; Matsui, William · Cell Stem Cell · 2009

editorial · Level V

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Abstract

The role of multiple developmental signaling pathways in the regulation of hematopoiesis has been controversial. In this issue of Cell Stem Cell, two separate reports (Hofmann et al., 2009; Gao et al., 2009) examine whether the Hedgehog signaling pathway modulates normal adult hematopoietic stem cells and blood formation.

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