Bone and blood vessels: the hard and the soft of hematopoietic stem cell niches.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 19497278.
- Also identified by DOI 10.1016/j.stem.2009.05.011.
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Abstract
Osteoblasts are important regulators of myelopoiesis and lymphopoiesis, producing several necessary soluble and membrane-associated factors. In addition, they may play important roles, along with other mesenchymal populations, in constructing an environment that is suitable for development of sinusoidal niches capable of supporting hematopoietic stem cells.
Medical subject headings
- Hematopoietic Stem Cells
- Stem Cell Niche