The Sequence Alignment/Map format and SAMtools.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 19505943.
- Also identified by DOI 10.1093/bioinformatics/btp352 and PMC identifier 2723002.
- Licence recorded as CC BY-NC.
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Abstract
The Sequence Alignment/Map (SAM) format is a generic alignment format for storing read alignments against reference sequences, supporting short and long reads (up to 128 Mbp) produced by different sequencing platforms. It is flexible in style, compact in size, efficient in random access and is the format in which alignments from the 1000 Genomes Project are released. SAMtools implements various utilities for post-processing alignments in the SAM format, such as indexing, variant caller and alignment viewer, and thus provides universal tools for processing read alignments. http://samtools.sourceforge.net.
Medical subject headings
- Computational Biology
- Sequence Alignment
- Sequence Analysis, DNA
- Software