Prevention of diabetes self-management program (PREDIAS): effects on weight, metabolic risk factors, and behavioral outcomes.

Abstract

To evaluate the efficacy of the group program PREDIAS for diabetes prevention. PREDIAS consists of 12 lessons and aims at lifestyle modification. The control group received written information about diabetes prevention. In this study, a total of 182 persons with an elevated diabetes risk participated (aged 56.3 +/- 10.1 years, 43% female, and BMI 31.5 +/- 5.3 kg/m(2)). After 12 months, weight loss was significantly higher (P = 0.001) in PREDIAS than in the control group (-3.8 +/- 5.2 vs. -1.4 +/- 4.09 kg). There were also significant effects (P = 0.001) on fasting glucose (control group 1.8 +/- 13.1 mg/dl vs. PREDIAS -4.3 +/- 11.3 mg/dl), duration of physical activity per week (control group 17.9 +/- 63.8 min vs. PREDIAS 46.6 +/- 95.5 min; P = 0.03), and eating behavior. PREDIAS significantly modified lifestyle factors associated with an elevated diabetes risk.