Pregnancy outcome in women with factor V Leiden and recurrent miscarriage.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 19522801.
- Also identified by DOI 10.1111/j.1471-0528.2009.02168.x.
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Abstract
We compared the outcome of 25 untreated pregnancies among women with recurrent miscarriage (RM) at <12 weeks' gestation who were heterozygous for factor V Leiden with women with unexplained RM. The livebirth rate was lower among pregnancies in carriers of factor V Leiden (12/25; 48%) compared with pregnancies in women with unexplained RM (175/307; 57%), but the difference did not reach statistical significance. The best possible treatment regimen to improve livebirth rate in this group of women needs to be assessed in the form of a randomised controlled trial.
Medical subject headings
- Abortion, Habitual
- Factor V
- Pregnancy Complications, Hematologic