Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population.
Level V
Where this comes from
- Record sourced from PubMed, PMID 19528989.
- Also identified by DOI 10.1038/ki.2009.130 and PMC identifier 4313549.
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Abstract
Progressive renal fibrosis is common to all chronic kidney diseases (CKD). Suthanthiran and colleagues identified a positive association between transforming growth factor-beta1 and several risk factors for CKD progression in African Americans but not in whites. This study offers a possible explanation for the higher prevalence of end-stage renal disease in African Americans and highlights the need for a better therapeutic strategy for this population.
Medical subject headings
- Black or African American
- Kidney Failure, Chronic
- Population Groups
- Transforming Growth Factor beta1